Arya Vaidyan P.V.Rama Varier was born in 1908 as the only son of Vaidyavichakshanan Mankulangara Kunjan Varier, a reputed Sanskrit scholar, poet and physician and Smt. Putiya Variyath Kutty Varasiar. He joined the Ayurvedic College at Kottakkal after his high school studies and was the trusted disciple of Vaidyaratnam P. S. Varier. Under the able guidance of his preceptor he was trained not only in the treatment of illnesses but also in the preparation of medicines. He was given the independent charge of the Calicut Branch of Kottakkal Arya Vaidya Sala in 1930, which he continued till 1943.

The thirteen years of his office under the able Guru found in him a trusted lieutenant, a well known Ayurvedic physician and a man reckoned with in various spheres of public activity. His deep knowledge, innate sincerity, humility and capacity for untiring hard work won for him the deep affection and trust of all those who came into contact with him. The affluent and congenial atmosphere of his life at Calicut could not fetter his restless soul which yearned for an independent life in dedication to the cause of Ayurveda. He resigned his job on 30th June 1943 and with his blessing of his Guru and good wishes of his colleagues set out on his new venture.